SCHEMBL6660002

SCHEMBL6660002

F[B-](F)(F)F.F[B-](F)(F)F.N#Cc1ccc(-[n+]2ccc(-c3cc[n+](-c4ccc(C#N)cc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 3/20 0.41
▸ MMP3 P08254 1/20 0.41
▸ CYP11B2 P19099 1/20 0.38
▸ HDAC8 Q9BY41 1/20 0.38
▸ CYP2A6 P11509 2/20 0.36
▸ ENPP2 Q13822 1/20 0.36
▸ CA12 O43570 2/20 0.35
▸ CA2 P00918 2/20 0.35
▸ CA9 Q16790 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ CA3 P07451 1/20 0.35
▸ CA6 P23280 1/20 0.35
▸ CA14 Q9ULX7 1/20 0.35
▸ CA1 P00915 1/20 0.35
▸ PTPN5 P54829 1/20 0.34
▸ TSHR P16473 2/20 0.33
▸ PTGS1 P23219 1/20 0.33
▸ GABRA1 P14867 1/20 0.33
▸ GABRG2 P18507 1/20 0.33
▸ GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4325064 0.92 MMP3 (0.46) KIF11MMP3CYP11B2HDAC8CYP2A6
Hydrochloric Acid SCHEMBL2463206 0.90 MMP3 (0.45) KIF11MMP3CYP11B2HDAC8CYP2A6
Bromide SCHEMBL10597082 0.90 MMP3 (0.45) KIF11MMP3CYP11B2HDAC8CYP2A6
SCHEMBL6660004 0.87 KIF11 (0.40) KIF11MMP3CYP11B2HDAC8CYP2A6
SCHEMBL19689478 0.83 HDAC8 (0.61) KIF11MMP3HDAC8CYP2A6ENPP2
Hydrochloric Acid SCHEMBL11601600 0.81 CYP11B2 (0.43) KIF11MMP3CYP11B2HDAC8
Hydrochloric Acid SCHEMBL11503645 0.80 CYP11B2 (0.42) KIF11MMP3CYP11B2
SCHEMBL12287094 0.79 MMP3 (0.36) KIF11MMP3CYP11B2HDAC8CYP2A6
Bromide SCHEMBL20544131 0.78 CYP2A6 (0.43) KIF11MMP3CYP11B2HDAC8CYP2A6
SCHEMBL16470406 0.75 TSHR (0.50) MMP3HDAC8CYP2A6ENPP2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11067867-B2 Electrochromic organic frameworks GENTEX CORPORATION (US) 2021-07-20 — — US disclosed
US-20180321565-A1 ELECTROCHROMIC ORGANIC FRAMEWORKS GENTEX CORPORATION (US) 2018-11-08 — — US disclosed
WO-2018204802-A1 ELECTROCHROMIC ORGANIC FRAMEWORKS GENTEX CORPORATION (US) 2018-11-08 — — WO disclosed
EP-0725305-B2 A variable reflectance mirror for an automobile GENTEX CORP (US) 2004-08-18 — — EP disclosed
US-6351328-B1 Variable transmittance electrochromic devices GENTEX CORPORATION 2002-02-26 — — US disclosed
US-6211994-B1 Variable transmittance electrochromic devices GENTEX CORPORATION 2001-04-03 — — US disclosed
US-6016215-A Variable transmittance electrochromic devices GENTEX CORPORATION (US) 2000-01-18 — — US disclosed
EP-0725305-B1 A variable reflectance mirror for an automobile GENTEX CORP (US) 1999-06-09 — — EP disclosed
US-5801873-A Variable reflectance automobile mirror GENTEX CORPORATION (US) 1998-09-01 — — US disclosed
US-5751467-A Variable reflectance automobile mirror GENTEX CORPORATION (US) 1998-05-12 — — US disclosed
EP-0240226-B1 Single-compartment, self-erasing, solution-phase electrochromic devices, solutions for use therein, and uses thereof GENTEX CORP (US) 1996-11-06 — — EP disclosed
EP-0725305-A2 A variable reflectance mirror for an automobile GENTEX CORPORATION (US) 1996-08-07 — — EP disclosed
US-5481395-A Prismatic variable reflectance mirrors GENTEX CORPORATION (US) 1996-01-02 — — US disclosed
US-5290930-A Transmittance of electromagnetic radiation GENTEX CORPORATION (US) 1994-03-01 — — US disclosed
US-5282077-A Compartment containing solution of electrochromic compounds GENTEX CORPORATION (US) 1994-01-25 — — US disclosed
US-5128799-A Variable reflectance motor vehicle mirror GENTEX CORPORATION (US) 1992-07-07 — — US disclosed
US-4902108-A REVERSE VARIABLE TRANSMITTANCE OF LIGHT GENTEX CORPORATION (US) 1990-02-20 — — US disclosed
EP-0240226-A2 Single-compartment, self-erasing, solution-phase electrochromic devices, solutions for use therein, and uses thereof GENTEX CORPORATION (US) 1987-10-07 — — EP disclosed
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