Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540168 | 0.86 | TSHR (0.46) | ESR1ESR2SRD5A2TSHRALDH1A1 | |
| SCHEMBL4814687 | 0.86 | CASP1 (0.53) | AKR1B1CASP1CASP7HSD17B10MAOA | |
| SCHEMBL31468782 | 0.83 | TRPA1 (0.36) | ESR1ESR2TSHRALDH1A1TRPA1 | |
| SCHEMBL29780668 | 0.77 | TSHR (0.59) | SRD5A2TSHRALDH1A1ATMNPSR1 | |
| SCHEMBL7974044 | 0.77 | TSHR (0.59) | SRD5A2TSHRALDH1A1ATMNPSR1 | |
| SCHEMBL7127913 | 0.76 | AKR1B1 (0.42) | AKR1B1SRD5A1SRD5A2TSHRPARP11 | |
| SCHEMBL3284644 | 0.76 | TSHR (0.42) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL11620189 | 0.76 | AKR1B1 (0.39) | AKR1B1SRD5A1SRD5A2TSHRALDH1A1 | |
| SCHEMBL3279449 | 0.74 | RXRB (0.42) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3453711 | 0.74 | SRD5A1 (0.45) | SRD5A1SRD5A2TSHRALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029332-B2 | Cross-linked peptides and proteins, methods of making same, and uses thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2015-05-12 | — | — | US | disclosed |
| US-9029332-B2 | Cross-linked peptides and proteins, methods of making same, and uses thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2015-05-12 | — | — | US | disclosed |
| US-20140057857-A1 | Cross-Linked Peptides and Proteins, Methods of Making Same, and Uses Thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057857-A1 | Cross-Linked Peptides and Proteins, Methods of Making Same, and Uses Thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2012083078-A2 | CROOS-LINKED PEPTIDES AND PROTEINS, METHODS OF MAKING SAME, AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2004003044-A2 | DYNAMERS: POLYMERIC MATERIALS EXHIBITING REVERSIBLE FORMATION AND COMPONENT EXCHANGE | LEHN JEAN-MARIE (FR) | 2004-01-08 | — | — | WO | disclosed |
| US-4096154-A | FORMING A SULFONIUM SALT BY REACTION OF A HALOGEN AS ESTER WITH AN ORGANIC SULFIDE | CIBA-GEIGY CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |
| US-4016203-A | Process for the manufacture of compounds containing vinyl groups | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140057857-A1 | Cross-Linked Peptides and Proteins, Methods of Making Same, and Uses Thereof | TIMCC, LCP1, DNPEP | AKR1B1 4362/4885ESR1 3528/4885ESR2 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.