Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660636 | 0.92 | HPRT1 (0.41) | ALDH1A1CYP2A6MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6660633 | 0.83 | NISCH (0.36) | NISCHALDH1A1CYP2A6ALOX5HPGD | |
| SCHEMBL6658256 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL3389230 | 0.72 | ALOX15 (0.37) | NISCHALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6656510 | 0.70 | GSTP1 (0.33) | NISCHALDH1A1CYP2A6ALOX5ALOX15 | |
| SCHEMBL25302086 | 0.65 | ALDH1A1 (0.59) | NISCHALDH1A1CYP2A6MAPTSMN1; SMN2 | |
| SCHEMBL29350007 | 0.65 | ALDH1A1 (0.59) | NISCHALDH1A1CYP2A6MAPTSMN1; SMN2 | |
| SCHEMBL27953 | 0.65 | ALDH1A1 (0.59) | NISCHALDH1A1CYP2A6MAPTSMN1; SMN2 | |
| SCHEMBL6930009 | 0.65 | HTR7 (0.39) | NISCHALDH1A1CYP2A6MAPTSMN1; SMN2 | |
| SCHEMBL6056141 | 0.65 | HTR7 (0.39) | NISCHALDH1A1CYP2A6MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050538-B1 | Irradiation-curable silicone compositions containing photo-active platinum (IV) compounds | GEN ELECTRIC (US) | 2004-08-04 | — | — | EP | disclosed |
| US-6150546-A | AS HYDROSILYLATION CATALYST FOR EFFECTING THE CURE OF AN IRRADIATION-CURABLE SILICONE MIXTURE | GENERAL ELECTRIC COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-1050538-A2 | Irradiation-curable silicone compositions containing photo-active platinum (IV) compounds | GENERAL ELECTRIC COMPANY (US) | 2000-11-08 | — | — | EP | disclosed |