Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865038 | 0.95 | NPC1 (0.45) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL31253883 | 0.89 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL4111905 | 0.89 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL13474908 | 0.89 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL9866271 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL6683177 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL8495073 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL6687308 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL15365285 | 0.81 | MAPT (0.40) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL3470252 | 0.81 | HTT (0.44) | ALDH1A1LMNAMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082138-B1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | UNIV TEXAS (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6207660-B1 | Texaphyrin conjugates and uses thereof | PHARMACYCLICS, INC. | 2001-03-27 | — | — | US | disclosed |
| EP-1082138-A1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999062551-A1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-12-09 | — | — | WO | disclosed |