Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661001 | 0.95 | ALDH1A1 (0.48) | NPC1RAB9ARECQLALDH1A1MAPT | |
| SCHEMBL15365285 | 0.84 | MAPT (0.40) | NPC1RAB9ARECQLALDH1A1MAPT | |
| SCHEMBL15365067 | 0.84 | MAPT (0.40) | NPC1RAB9ARECQLALDH1A1MAPT | |
| SCHEMBL3470252 | 0.84 | HTT (0.44) | NPC1ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL31253883 | 0.83 | ALDH1A1 (0.54) | NPC1RAB9ARECQLALDH1A1MAPT | |
| SCHEMBL13474908 | 0.83 | ALDH1A1 (0.54) | NPC1RAB9ARECQLALDH1A1MAPT | |
| SCHEMBL4111905 | 0.83 | ALDH1A1 (0.54) | NPC1RAB9ARECQLALDH1A1MAPT | |
| SCHEMBL9865389 | 0.83 | SNCA (0.44) | NPC1RAB9ARECQLALDH1A1MAPT | |
| SCHEMBL9866271 | 0.81 | ALDH1A1 (0.43) | NPC1RAB9ARECQLALDH1A1MAPT | |
| SCHEMBL6683177 | 0.80 | ALDH1A1 (0.48) | NPC1RAB9ARECQLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |