Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865389 | 0.91 | SNCA (0.44) | ALDH1A1MAPTMAPK1NPC1RECQL | |
| SCHEMBL13882647 | 0.91 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1NPC1 | |
| SCHEMBL6661001 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1NPC1 | |
| SCHEMBL19314044 | 0.85 | MAPT (0.38) | ALDH1A1LMNAMAPTMAPK1NPC1 | |
| SCHEMBL6683177 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1NPC1 | |
| SCHEMBL9865038 | 0.81 | NPC1 (0.45) | ALDH1A1LMNAMAPTMAPK1NPC1 | |
| SCHEMBL9864739 | 0.80 | LMNA (0.57) | ALDH1A1LMNAMAPTMAPK1RAB9A | |
| SCHEMBL17668974 | 0.77 | NPC1 (0.75) | ALDH1A1LMNAMAPTMAPK1NPC1 | |
| SCHEMBL17669136 | 0.77 | NPC1 (0.75) | ALDH1A1LMNAMAPTMAPK1NPC1 | |
| SCHEMBL19128338 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |