Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661444 | 1.00 | KDM4E (0.41) | KDM4EMAPK1TDP1CYP3A4CYP2C9 | |
| SCHEMBL6656248 | 0.84 | MGLL (0.37) | KDM4EMAPK1TDP1CYP3A4CYP2C9 | |
| SCHEMBL6656930 | 0.84 | MGLL (0.37) | KDM4EMAPK1TDP1CYP3A4CYP2C9 | |
| SCHEMBL6656284 | 0.82 | MGLL (0.35) | KDM4EMAPK1TDP1CYP3A4CYP2C9 | |
| SCHEMBL6656286 | 0.82 | MGLL (0.35) | KDM4EMAPK1TDP1CYP3A4CYP2C9 | |
| SCHEMBL7546325 | 0.73 | KDM4E (0.41) | KDM4EMAPK1TDP1CYP2C19MGLL | |
| SCHEMBL6662309 | 0.73 | LDHA (0.44) | KDM4EMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL6690262 | 0.73 | LDHA (0.44) | KDM4EMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL6661078 | 0.73 | LDHA (0.44) | KDM4EMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL917938 | 0.70 | NR5A1 (0.62) | KDM4ETDP1PLA2G4BNR5A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |