Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656284 | 1.00 | MGLL (0.35) | MGLLKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL6656930 | 0.92 | MGLL (0.37) | MGLLKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL6656248 | 0.92 | MGLL (0.37) | MGLLKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL6662265 | 0.82 | LDHA (0.38) | KDM4EMAPK1TDP1ALDH1A1PPARG | |
| SCHEMBL6661444 | 0.82 | KDM4E (0.41) | MGLLKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL6661442 | 0.82 | KDM4E (0.41) | MGLLKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL6657628 | 0.77 | NR5A1 (0.35) | TP53TSHRNR5A1PLA2G4BLTA4H | |
| SCHEMBL7915947 | 0.74 | SLC6A4 (0.39) | TP53TSHRPLA2G4BMAPTCYP3A4 | |
| SCHEMBL7546325 | 0.72 | KDM4E (0.41) | MGLLKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL6661829 | 0.72 | PTPN11 (0.45) | TP53TSHRPLA2G4BLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |