Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.63 |
| ▸ | TTR | P02766 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21635983 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL6659611 | 0.84 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL29361856 | 0.83 | ADORA2A (0.72) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL31560165 | 0.83 | MAOA (0.68) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL2770797 | 0.83 | MAOA (0.68) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL4444783 | 0.83 | ADORA2A (0.72) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL2770562 | 0.83 | MAOA (0.68) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL29928804 | 0.83 | MAOA (0.68) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL30377911 | 0.83 | ADORA2A (0.72) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR | |
| SCHEMBL8773084 | 0.83 | ADORA2A (0.72) | ALDH1A1SMN1; SMN2TDP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087935-B1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INT LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-20030203975-A1 | Anti-cancer agents | BTG INTERNATIONAL LIMITED (GB) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203975-A1 | Anti-cancer agents | TOP2B, TOP2A, TOP1 | ALDH1A1 3625/4885SMN1; SMN2 4126/4885TDP1 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.