Glutamic Acid

SCHEMBL6661749

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Histidine SCHEMBL6661753	0.90	—	—
Glutamic Acid SCHEMBL6664450	0.90	CMA1 (0.31)	—
Histidine SCHEMBL9294080	0.83	MC4R (0.31)	—
Histidine SCHEMBL5577952	0.83	—	—
Histidine SCHEMBL5577985	0.82	—	—
Histidine SCHEMBL9294075	0.81	—	—
Histidine SCHEMBL6664452	0.81	CMA1 (0.32)	—
Phenylalanine SCHEMBL1239596	0.80	GHSR (0.33)	—
Histidine SCHEMBL9031033	0.78	CRHR1 (0.32)	—
Leucine SCHEMBL2126472	0.78	SLC7A5 (0.34)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0840126-B1	Marker and immunological reagent for dialysis-related amyloidosis, diabetes mellitus and diabetes mellitus complications	TOKUYAMA CORP (JP)	2004-09-01	—	—	EP	disclosed
US-6033862-A	Marker and immunological reagent for dialysis-related amyloidosis, diabetes mellitus and diabetes mellitus complications	TOKUYAMA CORPORATION (JP)	2000-03-07	—	—	US	disclosed