Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661859 | 0.91 | ESR1 (0.36) | CACNA1HPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6661309 | 0.91 | CACNA1H (0.34) | CACNA1HPDE4APDE2A | |
| SCHEMBL6664047 | 0.87 | GPR84 (0.30) | GPR84SENP8SENP7SENP6 | |
| SCHEMBL6666745 | 0.84 | PDE2A (0.37) | CACNA1HPDE2A | |
| SCHEMBL6665134 | 0.82 | MAOA (0.35) | GPR84SENP8SENP7SENP6 | |
| SCHEMBL6663312 | 0.81 | PPARG (0.39) | — | |
| SCHEMBL6662183 | 0.81 | GPR84 (0.34) | GPR84SENP8SENP7SENP6 | |
| SCHEMBL6666029 | 0.80 | CYP2C9 (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6662213 | 0.79 | ESR1 (0.36) | — | |
| SCHEMBL6661998 | 0.79 | CACNA1H (0.36) | CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |