Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6662101

CCCCCC[n+]1ccn(C)c1.O=C([O-])C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
HSP90AA1 P07900 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
APAF1 O14727 1/20 0.38
RGS12 O14924 1/20 0.38
MAPK1 P28482 1/20 0.38
FDPS P14324 6/20 0.38
CCR5 P51681 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3764707 1.00 MEN1 (0.41) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Trifluoroacetic Acid SCHEMBL302072 0.94 MEN1 (0.37) MEN1HSP90AA1KMT2ASMN1; SMN2FDPS
Bicarbonate SCHEMBL28733245 0.90 MEN1 (0.46) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bicarbonate SCHEMBL28939212 0.90 MEN1 (0.46) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bicarbonate SCHEMBL23698465 0.88 ABCB11 (0.44) MEN1HSP90AA1KMT2ASMN1; SMN2
Bicarbonate SCHEMBL23698462 0.88 ABCB11 (0.44) MEN1HSP90AA1KMT2ASMN1; SMN2
Acetic Acid SCHEMBL3140598 0.88 MEN1 (0.48) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Acetic Acid SCHEMBL23004170 0.88 MEN1 (0.48) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Acetic Acid SCHEMBL21178431 0.88 MEN1 (0.48) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bicarbonate SCHEMBL6265469 0.88 MEN1 (0.44) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1241156-B1 Process for the hydroformylation of olefinic unsaturated compounds in a non-aqueous ionic solvent INST FRANCAIS DU PETROLE (FR) 2004-08-18 EP claimed
US-6617474-B2 Reacting olefinically unsaturated compound with carbon monoxide and hydrogen in presence of polar phase comprising: a non-aqueous ionic liquid comprising quaternary ammonium and/or a quaternary phosphonium compound and catalyst; adding solvent INSTITUT FRANCAIS DU PETROLE (FR) 2003-09-09 US claimed
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent INSTITUT FRANCAIS DU PETROLE (FR) 2002-07-25 US claimed
US-20260106558-A1 TRIBOELECTRIC NANOGENERATOR AND OPERATION METHOD THEREOF UNIV NAT TAIWAN (TW) 2026-04-16 US disclosed
CN-112608689-B Antistatic organic silicon pressure-sensitive adhesive containing electron transport material and preparation method thereof 浙江工业大学 2022-05-20 CN disclosed
CN-112608689-A Antistatic organic silicon pressure-sensitive adhesive containing electron transport material and preparation method thereof 浙江工业大学 2021-04-06 CN disclosed
US-6617474-B2 Reacting olefinically unsaturated compound with carbon monoxide and hydrogen in presence of polar phase comprising: a non-aqueous ionic liquid comprising quaternary ammonium and/or a quaternary phosphonium compound and catalyst; adding solvent INSTITUT FRANCAIS DU PETROLE (FR) 2003-09-09 US disclosed
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent INSTITUT FRANCAIS DU PETROLE (FR) 2002-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260106558-A1 TRIBOELECTRIC NANOGENERATOR AND OPERATION METHOD THEREOF FTO, RPL13, DCX MEN1 4858/4885HSP90AA1 2303/4885KMT2A 4606/4885
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent NUDT1, PHOSPHO1, SRSF6 MEN1 3137/4885HSP90AA1 2906/4885KMT2A 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.