Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657784 | 0.97 | SLC6A5 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6660359 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL28150718 | 0.75 | OPRM1 (0.35) | — | |
| SCHEMBL6659991 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL6658153 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL6657779 | 0.71 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6660791 | 0.70 | — | — | |
| Bromide SCHEMBL6656297 | 0.67 | — | — | |
| SCHEMBL6658157 | 0.66 | CETP (0.30) | — | |
| SCHEMBL21320563 | 0.65 | PLA2G1B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160267-B1 | CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE | JAPAN SCIENCE & TECH CORP (JP) | 2004-08-04 | — | — | EP | disclosed |