Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.65 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602946 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1KEAP1PPARA | |
| SCHEMBL1748171 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1KEAP1PPARA | |
| SCHEMBL31214029 | 0.85 | FBP1 (0.58) | SMN1; SMN2NPSR1KEAP1PPARAF2RL3 | |
| SCHEMBL25386895 | 0.82 | FBP1 (0.55) | SMN1; SMN2NPSR1KEAP1PPARAF2RL3 | |
| SCHEMBL7867881 | 0.80 | KEAP1 (0.67) | SMN1; SMN2NPSR1KEAP1PKMF2RL3 | |
| SCHEMBL30602949 | 0.80 | KEAP1 (0.67) | SMN1; SMN2NPSR1KEAP1PKMF2RL3 | |
| SCHEMBL1622148 | 0.79 | KEAP1 (0.65) | SMN1; SMN2NPSR1KEAP1PPARAPKM | |
| SCHEMBL14327113 | 0.79 | KEAP1 (0.65) | SMN1; SMN2NPSR1KEAP1PKMMEN1 | |
| SCHEMBL304698 | 0.79 | KEAP1 (1.00) | SMN1; SMN2NPSR1KEAP1PKMMEN1 | |
| SCHEMBL1095273 | 0.79 | KEAP1 (0.65) | SMN1; SMN2NPSR1KEAP1PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116926578-A | Method for synthesizing heteroaryl thiophenol | 新疆大学 | 2023-10-24 | — | — | CN | disclosed |
| US-10189830-B2 | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
| WO-2004010761-A2 | PESTICIDAL CYANINE DYE DERIVATIVES | FMC CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189830-B2 | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders | NQO1, COQ8A, NDUFAB1 | SMN1; SMN2 303/4885NPSR1 3338/4885KEAP1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.