Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27270853 | 0.92 | GSTP1 (0.54) | GSTP1PPARGPPARAFFAR1NAAA | |
| SCHEMBL9397994 | 0.90 | DRD2 (0.51) | DRD2DRD4DRD3MAOBAPP | |
| SCHEMBL9478672 | 0.88 | MAOB (0.56) | DRD4MAOBAPPFOXM1NR4A2 | |
| SCHEMBL10713484 | 0.87 | TSHR (0.54) | GSTP1CYP1A2MAOBFOXM1BCHE | |
| SCHEMBL9793416 | 0.84 | GSTP1 (0.48) | GSTP1DRD2DRD4DRD3APP | |
| SCHEMBL9842913 | 0.84 | RXRA (0.49) | GSTP1PPARGPPARAFFAR1LSS | |
| SCHEMBL9478520 | 0.81 | KCNA3 (0.56) | DRD4MAOBAPPBCHEFFAR1 | |
| SCHEMBL6375370 | 0.80 | SRD5A2 (0.58) | MAOBPPARGPPARANR4A2ALDH1A1 | |
| SCHEMBL16594362 | 0.79 | TSHR (0.56) | CYP1A2MAOBAPPFOXM1BCHE | |
| SCHEMBL5725683 | 0.78 | L3MBTL1 (0.62) | MAOBPPARGNR4A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183224-B1 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | APPLETON PAPER INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1183224-A4 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | APPLETON PAPER INC (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-1183224-A1 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | Appleton Papers Inc. (GB) | 2002-03-06 | — | — | EP | disclosed |
| US-20020002311-A1 | Process for preparing alkoxy or arylmethoxy aroxyethanes | APPLETON PAPERS INC. | 2002-01-03 | — | — | US | disclosed |
| US-6323376-B1 | REACTING SUBSTITUTED OR UNSUBSTITUTED PHENOLS OR NAPHTHOLS WITH ETHYLENE CARBONATE IN PRESENCE OF CATALYST SELECTED FROM METAL HALIDE, QUARTERNARY AMMONIUM HALIDE AND QUARTERNARY PHOSPHONIUM HALIDE; REACTING INTERMEDIATE ARALKYL HALIDE | APPLETON PAPERS INC. | 2001-11-27 | — | — | US | disclosed |
| WO-2001060775-A1 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | APPLETON PAPERS INC. (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002311-A1 | Process for preparing alkoxy or arylmethoxy aroxyethanes | ARSA, PHYKPL, CCNY | ADAMTS5 4815/4885GSTP1 2798/4885GPR34 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.