Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666467 | 0.87 | TOP1 (0.44) | TOP1NPC1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL6659626 | 0.84 | TOP1 (0.59) | TOP1L3MBTL1MAPK1KDM4EALDH1A1 | |
| SCHEMBL7610922 | 0.83 | ACACA (0.53) | TOP1NPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL20910379 | 0.75 | MEN1 (0.56) | NPC1SMN1; SMN2L3MBTL1MEN1PKM | |
| SCHEMBL6663329 | 0.74 | ESR1 (0.69) | MEN1MAPK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6667127 | 0.74 | ESR1 (0.54) | MEN1KMT2AMAPTELANEADORA2A | |
| SCHEMBL8956454 | 0.74 | MAPK1 (0.63) | NPC1SMN1; SMN2L3MBTL1MEN1MAPK1 | |
| SCHEMBL28252108 | 0.73 | ACHE (0.54) | TOP1SMN1; SMN2L3MBTL1MAPK1KDM4E | |
| SCHEMBL20910594 | 0.73 | NPC1 (0.46) | NPC1SMN1; SMN2L3MBTL1MEN1PKM | |
| SCHEMBL440455 | 0.73 | MAP4K1 (0.49) | TOP1NPC1SMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861864-B1 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-20020151659-A1 | Formed from 6,6'-bis(2-(4-fluorophenyl)-4- phenylquinoline) and 4,4'-(1,1,1,3,3,3-hexafluoro-2,2-propylidene)bisphenol and 2,2-bis((4-maleimidophenoxy)phenyl)propane; dielectrics | HITACHI CHEMICAL CO., LTD. (JP) | 2002-10-17 | — | — | US | disclosed |
| US-6462148-B1 | RESIN COMPOSITION COMPRISING A POLYMER CONTAINING A QUINOLINE RING AND A THERMOSETTING RESIN, AN INSULATING MATERIAL CONSTITUTED BY SAID RESIN COMPOSITION AND AN ADHESIVE FILM, PARTICULARLY A RESIN FOR AN INTERLAYER INSULATION FILM | HITACHI CHEMICAL CO., LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| JP-2001002898-A | RESIN COMPOSITION AND INSULATING COATING FILM USING THE SAME | HITACHI CHEM CO LTD | 2001-01-09 | — | — | JP | disclosed |
| JP-2001002900-A | RESIN COMPOSITION AND INSULATING COATING FILM USING THE SAME | HITACHI CHEM CO LTD | 2001-01-09 | — | — | JP | disclosed |
| JP-2001002899-A | RESIN COMPOSITION AND INSULATING COATING FILM USING THE SAME | HITACHI CHEM CO LTD | 2001-01-09 | — | — | JP | disclosed |
| JP-2001002897-A | RESIN COMPOSITION AND INSULATING COATING FILM USING THE SAME | HITACHI CHEM CO LTD | 2001-01-09 | — | — | JP | disclosed |
| US-6132852-A | LAMINATE OF POLYMER CONDUCTOR AND DIELECTRIC | HITACHI, LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0861864-A2 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5786071-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5648448-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-07-15 | — | — | US | disclosed |