⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123688 | 1.00 | — | — | |
| SCHEMBL7434698 | 0.81 | TAAR1 (0.63) | — | |
| SCHEMBL646951 | 0.81 | ALDH1A1 (0.43) | — | |
| SCHEMBL94761 | 0.80 | — | — | |
| SCHEMBL3300276 | 0.79 | PNMT (0.65) | — | |
| SCHEMBL12050856 | 0.79 | TAAR1 (0.74) | — | |
| SCHEMBL14691406 | 0.78 | TAAR1 (0.59) | — | |
| SCHEMBL195102 | 0.77 | — | — | |
| SCHEMBL30181552 | 0.77 | — | — | |
| SCHEMBL29355341 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2023-01-19 | — | — | US | disclosed |
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2023-01-19 | — | — | US | disclosed |
| CN-113149971-B | 8- (indoletriazole) substituted coumarin compound and preparation method and application thereof | 港科鹏禾生物(苏州)有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113149971-A | 8- (indoletriazole) substituted coumarin compound and preparation method and application thereof | 港科鹏禾生物(苏州)有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20210198237-A1 | PIPERIDINES AS MENIN INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2021-07-01 | — | — | US | disclosed |
| WO-2021038292-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
| WO-2021038292-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
| EP-3353167-B1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-06-24 | — | — | EP | disclosed |
| US-10647687-B2 | Spiropyrazine derivatives as inhibitors of non-apoptotic regulated cell-death | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2020-05-12 | — | — | US | disclosed |
| US-20190152947-A1 | PIPERIDINES AS MENIN INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-05-23 | — | — | US | disclosed |
| WO-2015080940-A1 | A3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-06-04 | — | — | WO | disclosed |
| EP-2763200-A1 | THERMOELECTRIC CONVERSION MATERIAL AND THERMOELECTRIC CONVERSION ELEMENT | FUJI-FILM Corporation (JP) | 2014-08-06 | — | — | EP | disclosed |
| WO-2014063642-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | 中国中化股份有限公司 (CN) | 2014-05-01 | — | — | WO | disclosed |
| EP-1159314-B1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEM CO (US) | 2004-08-04 | — | — | EP | disclosed |
| CN-1138793-C | Process for producing polyethylene | �Ϻ���ͨ��ѧ | 2004-02-18 | — | — | CN | disclosed |
| US-6534613-B2 | Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst | EASTMAN CHEMICAL COMPANY | 2003-03-18 | — | — | US | disclosed |
| CN-1332753-A | Process for producing polyethylene | EASTMAN CHEM CO (US) | 2002-01-23 | — | — | CN | disclosed |
| US-20020007024-A1 | Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst | WESTLAKE LONGVIEW CORPORATION | 2002-01-17 | — | — | US | disclosed |
| EP-1159314-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000052067-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |