Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220188 | 0.91 | AADAT (0.47) | ELANEBRD4CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL6908820 | 0.82 | ELANE (0.50) | ELANEBRD4CSNK2A1PLK1PLK3 | |
| SCHEMBL6837137 | 0.82 | NPBWR1 (0.51) | ELANECSNK2A1PLK1PLK3CSNK2A2 | |
| SCHEMBL20439112 | 0.82 | SMN1; SMN2 (0.46) | ELANEBRD4CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL20423850 | 0.79 | AADAT (0.40) | ELANEHTTLMNAAADATRECQL | |
| SCHEMBL20458076 | 0.79 | AADAT (0.40) | ELANEBRD4HTTLMNAAADAT | |
| SCHEMBL20423851 | 0.79 | AADAT (0.40) | ELANEHTTLMNAAADATRECQL | |
| SCHEMBL9142953 | 0.76 | PLK1 (0.62) | ELANEBRD4CSNK2A1PLK1PLK3 | |
| SCHEMBL30768728 | 0.76 | PKM (0.44) | ELANEBRD4CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL9222643 | 0.74 | AADAT (0.44) | HTTLMNAAADATRECQLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357914-B1 | AROMATIC COMPOUND PRODUCTION METHOD | FUJIFILM CORP (JP) | 2019-11-20 | — | — | EP | disclosed |
| US-10323005-B2 | Aromatic compound production method | FUJIFILM CORPORATION (JP) | 2019-06-18 | — | — | US | disclosed |
| EP-3357914-A1 | AROMATIC COMPOUND PRODUCTION METHOD | FUJIFILM Corporation (JP) | 2018-08-08 | — | — | EP | disclosed |
| US-20180215716-A1 | AROMATIC COMPOUND PRODUCTION METHOD | FUJIFILM CORPORATION (JP) | 2018-08-02 | — | — | US | disclosed |
| US-20180215716-A1 | AROMATIC COMPOUND PRODUCTION METHOD | FUJIFILM CORPORATION (JP) | 2018-08-02 | — | — | US | disclosed |
| EP-1476431-A1 | TRICYCLIC PYRAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003070706-A1 | TRICYCLIC PYRAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2003-08-28 | — | — | WO | disclosed |
| EP-0590558-B1 | Pharmaceutical composition containing 1,5,6,7-tetrahydro-4H-indazol-4-ones,new 1,5,6,7-tetrahydro-4H-indazol-4-ones and process for their manufacture | THOMAE GMBH DR K (DE) | 1995-12-06 | — | — | EP | disclosed |
| US-5468766-A | Analgesics, antipyretics, antiphlogistics | DR. KARL THOMAE GMBH (DE) | 1995-11-21 | — | — | US | disclosed |
| EP-0276833-B1 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMA (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0590558-A1 | Pharmaceutical composition containing 1,5,6,7-tetrahydro-4H-indazol-4-ones,new 1,5,6,7-tetrahydro-4H-indazol-4-ones and process for their manufacture | Dr. Karl Thomae GmbH (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0276833-A2 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4734430-A | Dipyrazoles and their use as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215716-A1 | AROMATIC COMPOUND PRODUCTION METHOD | PAH, AHR, TYR | ELANE 4811/4885BRD4 861/4885CSNK2A1 4450/4885 |
| US-10323005-B2 | Aromatic compound production method | PAH, AHR, TYR | ELANE 4811/4885BRD4 861/4885CSNK2A1 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.