Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766101 | 0.86 | PPARA (0.59) | PPARAPPARGCTSKTDP1CTSL | |
| SCHEMBL1447017 | 0.86 | PPARA (0.59) | PPARAPPARGCTSKTDP1CTSL | |
| SCHEMBL5089560 | 0.86 | CTSK (0.45) | PPARASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL5086244 | 0.86 | CTSK (0.45) | PPARASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL5001274 | 0.80 | PPARA (0.67) | PPARALMNAPPARGCTSKCTSS | |
| SCHEMBL5001271 | 0.80 | PPARA (0.67) | PPARALMNAPPARGCTSKCTSS | |
| SCHEMBL16582478 | 0.79 | CTSL (0.57) | PPARACTSKCTSLCTSSSIRT2 | |
| SCHEMBL12879969 | 0.79 | CTSL (0.57) | PPARACTSKCTSLCTSSSIRT2 | |
| SCHEMBL15156902 | 0.78 | SIRT2 (0.54) | PPARACTSKTDP1CTSLCTSS | |
| SCHEMBL12606001 | 0.77 | EPHX1 (0.41) | SMN1; SMN2NPC1RAB9ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014882-A2 | PROTEASOME INHIBITORS : PEPTIDE DERIVATIVES HAVING C-TERMINAL HETEROARYL GROUPS | AXYS PHARMACEUTICALS (US) | 2004-02-19 | — | — | WO | disclosed |