SCHEMBL6664063

SCHEMBL6664063

CCc1ccc(COC(F)(F)Cc2cc(F)c(OC(F)(F)F)c(F)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 3/20 0.34
TSHR P16473 1/20 0.32
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
TUBB1 Q9H4B7 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
SCN10A Q9Y5Y9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663209 0.89 GPR84 (0.32) FFAR4
SCHEMBL6661956 0.85 ESR1 (0.38) TP53
SCHEMBL6663003 0.85 MAOB (0.34) FFAR4
SCHEMBL6666327 0.84 PDE2A (0.38) PPARDPPARA
SCHEMBL6661347 0.83 FFAR4 (0.33) FFAR4
SCHEMBL6662056 0.82 FFAR4 (0.33) FFAR4
SCHEMBL6664138 0.82 MAOA (0.36) FFAR4
SCHEMBL6664949 0.80 TSHR (0.45) TSHRTP53MAPT
SCHEMBL21252850 0.79 PTGS2 (0.42) FFAR4TSHRPPARDPPARAMRGPRX4
SCHEMBL6665473 0.79 CYP2C9 (0.39) FFAR4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed