Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665134 | 0.89 | MAOA (0.35) | MAOAMAOBRIPK1ALDH1A1HTT | |
| SCHEMBL6663003 | 0.87 | MAOB (0.34) | MAOBRIPK1FFAR4RXRALMNA | |
| SCHEMBL6667082 | 0.86 | KIF11 (0.41) | FFAR4RXRAGRIN1GRIN2B | |
| SCHEMBL6663951 | 0.85 | ESR1 (0.42) | ALDH1A1LMNAACHECYP3A4 | |
| SCHEMBL6662056 | 0.84 | FFAR4 (0.33) | FFAR4LMNATAAR1PTPN1GAA | |
| SCHEMBL6666327 | 0.84 | PDE2A (0.38) | — | |
| SCHEMBL6665025 | 0.83 | TRPV4 (0.41) | MAOAMAOBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6664063 | 0.82 | FFAR4 (0.34) | FFAR4 | |
| SCHEMBL6661309 | 0.82 | CACNA1H (0.34) | ALDH1A1LMNAGAA | |
| SCHEMBL6667004 | 0.81 | LMNA (0.47) | MAOBALDH1A1LMNAPTPN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |