Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258068 | 1.00 | LMNA (0.52) | LMNAGPR84FFAR1PRSS1PRSS2 | |
| SCHEMBL10799754 | 1.00 | LMNA (0.52) | LMNAGPR84FFAR1PRSS1PRSS2 | |
| Glycerin SCHEMBL8428132 | 0.95 | LMNA (0.50) | LMNAGPR84FFAR1PRSS1PRSS2 | |
| SCHEMBL15535463 | 0.95 | LMNA (0.46) | LMNAGPR84FFAR1PRSS1PRSS2 | |
| Mannitol SCHEMBL8425772 | 0.92 | LMNA (0.44) | LMNAGPR84FFAR1PRSS1PRSS2 | |
| SCHEMBL1695574 | 0.89 | GPR84 (0.55) | LMNAGPR84FFAR1PRSS1PRSS2 | |
| SCHEMBL187080 | 0.86 | CYP3A4 (0.60) | LMNAPRSS1PRSS2PRSS3TSHR | |
| SCHEMBL11654426 | 0.84 | PRSS1 (0.50) | LMNAGPR84FFAR1PRSS1PRSS2 | |
| SCHEMBL11658392 | 0.84 | PRSS1 (0.50) | LMNAGPR84FFAR1PRSS1PRSS2 | |
| SCHEMBL2036656 | 0.83 | RECQL (0.51) | LMNAGPR84FFAR1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122297-B1 | Lubricant composition | ASAHI DENKA KOGYO KK (JP) | 2004-08-11 | — | — | EP | disclosed |
| EP-1122297-A2 | Lubricant composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 2001-08-08 | — | — | EP | disclosed |