Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799754 | 0.92 | LMNA (0.52) | LMNAPRSS1PRSS2PRSS3GPR84 | |
| SCHEMBL258068 | 0.92 | LMNA (0.52) | LMNAPRSS1PRSS2PRSS3GPR84 | |
| SCHEMBL6664875 | 0.92 | LMNA (0.52) | LMNAPRSS1PRSS2PRSS3GPR84 | |
| Glycerin SCHEMBL8428132 | 0.88 | LMNA (0.50) | LMNAPRSS1PRSS2PRSS3GPR84 | |
| SCHEMBL15535463 | 0.88 | LMNA (0.46) | LMNAPRSS1PRSS2PRSS3GPR84 | |
| SCHEMBL1695574 | 0.82 | GPR84 (0.55) | LMNAPRSS1PRSS2PRSS3GPR84 | |
| SCHEMBL8987469 | 0.81 | LMNA (0.40) | LMNAPRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL8987290 | 0.81 | LMNA (0.40) | LMNAPRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL187080 | 0.80 | CYP3A4 (0.60) | LMNAPRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL8987386 | 0.79 | LMNA (0.38) | LMNAPRSS1PRSS2PRSS3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512270-B1 | Cosmetic composition | KAO CORP (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0512270-A2 | Cosmetic composition | KAO CORPORATION (JP) | 1992-11-11 | — | — | EP | disclosed |