SCHEMBL258068

SCHEMBL258068

CCCCCCCCCC(CCCCCCC)COC(=O)C(O)CO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
GPR84 Q9NQS5 4/20 0.47
FFAR1 O14842 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
KDM4E B2RXH2 1/20 0.46
DUSP3 P51452 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TSHR P16473 2/20 0.44
CYP3A4 P08684 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ZDHHC7 Q9NXF8 1/20 0.42
MAPT P10636 1/20 0.41
SPHK1 Q9NYA1 1/20 0.41
GMNN O75496 1/20 0.41
POLB P06746 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6664875 1.00 LMNA (0.52) LMNAGPR84FFAR1PRSS1PRSS2
SCHEMBL10799754 1.00 LMNA (0.52) LMNAGPR84FFAR1PRSS1PRSS2
Glycerin SCHEMBL8428132 0.95 LMNA (0.50) LMNAGPR84FFAR1PRSS1PRSS2
SCHEMBL15535463 0.95 LMNA (0.46) LMNAGPR84FFAR1PRSS1PRSS2
Mannitol SCHEMBL8425772 0.92 LMNA (0.44) LMNAGPR84FFAR1PRSS1PRSS2
SCHEMBL1695574 0.89 GPR84 (0.55) LMNAGPR84FFAR1PRSS1PRSS2
SCHEMBL187080 0.86 CYP3A4 (0.60) LMNAPRSS1PRSS2PRSS3TSHR
SCHEMBL11654426 0.84 PRSS1 (0.50) LMNAGPR84FFAR1PRSS1PRSS2
SCHEMBL11658392 0.84 PRSS1 (0.50) LMNAGPR84FFAR1PRSS1PRSS2
SCHEMBL2036656 0.83 RECQL (0.51) LMNAGPR84FFAR1PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117915887-A Cleaning agent 株式会社资生堂 2024-04-19 CN disclosed
CN-117794499-A Capsule cosmetic 株式会社资生堂 2024-03-29 CN disclosed
US-7968607-B2 Cosmetics 1-isostearylglycerol-3-Sulfate Sodium Salt, used for constriction of keratinocytes; aging resistance KOA CORPORATION (JP) 2011-06-28 US disclosed
EP-1325737-B1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS KAO CORP (JP) 2009-12-16 EP disclosed
US-20080234390-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS KAO CORPORATION (JP) 2008-09-25 US disclosed
US-20040009140-A1 Skin pore minimizers and skin elasticity improvers KAO CORPORATION (JP) 2004-01-15 US disclosed
EP-1325737-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS Kao Corporation (JP) 2003-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040009140-A1 Skin pore minimizers and skin elasticity improvers CUTA, DSG1, OGA LMNA 2634/4885GPR84 2156/4885FFAR1 113/4885
US-20080234390-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS DSG1, CUTA, OGA LMNA 2681/4885GPR84 1987/4885FFAR1 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.