Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 8/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661244 | 0.91 | DAO (0.39) | DAOTRPV4RORCKDM1ACACNA1H | |
| SCHEMBL6666053 | 0.88 | TSHR (0.39) | DAOTRPV4RORCKDM1ACACNA1H | |
| SCHEMBL6663192 | 0.86 | CYP2A6 (0.35) | TRPV4CACNA1HCYP2A6 | |
| SCHEMBL6664131 | 0.84 | KIF11 (0.33) | DAO | |
| SCHEMBL7730247 | 0.83 | DAO (0.40) | DAOTRPV4RORCCACNA1HCYP11B1 | |
| SCHEMBL6661202 | 0.82 | ALDH1A1 (0.37) | DAORORCKDM1A | |
| SCHEMBL6662997 | 0.81 | KIF11 (0.33) | — | |
| SCHEMBL6667080 | 0.81 | DAO (0.40) | DAOCYP11B1CYP11B2 | |
| SCHEMBL6661164 | 0.80 | CYP2A6 (0.54) | DAOKCNJ1KCNH2CYP2A6 | |
| SCHEMBL6667092 | 0.80 | SPHK1 (0.35) | RORCKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |