Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | APOB | P04114 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6670752 | 0.99 | S1PR1 (0.43) | S1PR1S1PR3LMNASMOCFTR | |
| SCHEMBL6665956 | 0.83 | RXFP1 (0.41) | S1PR1S1PR3LMNACFTRPDE7A | |
| SCHEMBL6665641 | 0.83 | APOB (0.51) | SMOAPOBMTTP | |
| Hydrochloric Acid SCHEMBL6662670 | 0.82 | APOB (0.50) | SMOAPOBMTTP | |
| SCHEMBL6662272 | 0.82 | L3MBTL1 (0.51) | LMNACFTRPDE7AAPOBMTTP | |
| Hydrochloric Acid SCHEMBL6664266 | 0.81 | L3MBTL1 (0.50) | LMNACFTRPDE7AAPOBMTTP | |
| SCHEMBL6668677 | 0.79 | TP53 (0.53) | S1PR1S1PR3LMNAPDE7A | |
| SCHEMBL6683660 | 0.78 | S1PR1 (0.48) | S1PR1S1PR3LMNA | |
| SCHEMBL6645543 | 0.78 | MTTP (0.61) | LMNASMOAPOBMTTP | |
| SCHEMBL6803896 | 0.78 | APOB (0.51) | SMOAPOBMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |