Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 11/20 | 0.51 |
| ▸ | MTTP | P55157 | 10/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | SMO | Q99835 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6662670 | 0.99 | APOB (0.50) | APOBMTTPRXFP1SMOMAPK14 | |
| SCHEMBL6645543 | 0.89 | MTTP (0.61) | APOBMTTPSMOTP53 | |
| Hydrochloric Acid SCHEMBL6803931 | 0.88 | MTTP (0.60) | APOBMTTPSMOTP53 | |
| SCHEMBL6801574 | 0.87 | APOB (0.49) | APOBMTTPRXFP1PARP10PARP11 | |
| SCHEMBL6662272 | 0.84 | L3MBTL1 (0.51) | APOBMTTPPARP10PARP11TP53 | |
| Hydrochloric Acid SCHEMBL6664266 | 0.83 | L3MBTL1 (0.50) | APOBMTTPTP53 | |
| SCHEMBL6665124 | 0.83 | S1PR1 (0.44) | APOBMTTPSMO | |
| Hydrochloric Acid SCHEMBL6670752 | 0.82 | S1PR1 (0.43) | APOBMTTPSMO | |
| SCHEMBL6665956 | 0.82 | RXFP1 (0.41) | APOBMTTPRXFP1MAPK14TP53 | |
| SCHEMBL6665172 | 0.82 | GAA (0.54) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |