Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360572 | 0.95 | LTA4H (0.53) | LTA4HALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL2360573 | 0.95 | LTA4H (0.53) | LTA4HALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL6664833 | 0.85 | MAOB (0.58) | LTA4HTSHRIDO1AGXTMAOB | |
| SCHEMBL6667094 | 0.83 | MAOB (0.54) | ALDH1A1SMN1; SMN2HTTKDM4ESIGMAR1 | |
| SCHEMBL9618106 | 0.81 | MAOB (0.43) | LTA4HIDO1AGXTTRPA1MAOB | |
| SCHEMBL6666271 | 0.81 | MAOB (0.48) | LTA4HSMN1; SMN2HTTMAOB | |
| SCHEMBL5598799 | 0.80 | ALDH1A1 (0.59) | LTA4HALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL7921584 | 0.80 | ALDH1A1 (0.59) | LTA4HALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL11437812 | 0.79 | ALDH1A1 (0.68) | LTA4HALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL15105021 | 0.77 | TRPA1 (0.63) | LTA4HALDH1A1SMN1; SMN2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |