Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398503 | 0.75 | BMP1 (0.52) | TAS2R14L3MBTL1CA1CA2CA9 | |
| SCHEMBL6341748 | 0.74 | GRM2 (0.47) | GRM2GRM3CA1CA2CA7 | |
| SCHEMBL27925870 | 0.73 | GRM2 (0.58) | GRM2GRM3TAAR1CHRM2CHRM1 | |
| SCHEMBL28026558 | 0.73 | SMN1; SMN2 (0.49) | TAS2R14L3MBTL1CA9PKMMMP13 | |
| SCHEMBL28026557 | 0.73 | SMN1; SMN2 (0.49) | TAS2R14L3MBTL1CA9PKMMMP13 | |
| SCHEMBL7539405 | 0.73 | PKM (0.50) | TAS2R14L3MBTL1CA1CA2CA7 | |
| SCHEMBL6963146 | 0.73 | BCHE (0.58) | TAS2R14L3MBTL1CA1CA2CA7 | |
| SCHEMBL2761358 | 0.73 | HTT (0.55) | PKMMMP13 | |
| SCHEMBL28246110 | 0.72 | GRM2 (0.57) | GRM2GRM3TMEM97TAAR1CHRM2 | |
| SCHEMBL3397090 | 0.72 | ALDH1A1 (0.62) | TAS2R14CA1CA2CA9BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409468-A2 | GUANIDINOBENZAMIDES AS MC4-R AGONISTS | CHIRON CORPORATION (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002018327-A2 | GUANIDINOBENZAMIDES AS MC4-R AGONISTS | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |