Hydrochloric Acid

Hydrochloric Acid

SCHEMBL867181

Cl.Cl.Nc1ccc2c(c1)Cc1cc(N)ccc1-2

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA known ✓ P10253 2/20 0.47
PARP1 known ✓ P09874 1/20 0.43
KCNH2 known ✓ Q12809 1/20 0.40
GLA known ✓ P06280 1/20 0.39
LCK known ✓ P06239 1/20 0.39
ESR1 known ✓ P03372 1/20 0.38
ESR2 known ✓ Q92731 1/20 0.38
RAB9A P51151 6/20 0.75
MAPT P10636 4/20 0.75
NPC1 O15118 4/20 0.75
LMNA P02545 3/20 0.75
ALDH1A1 P00352 3/20 0.75
SMN1; SMN2 Q16637 3/20 0.75
KDM4E B2RXH2 2/20 0.75
HPGD P15428 2/20 0.75
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
TLR9 Q9NR96 1/20 0.60
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17417855 1.00 RAB9A (0.75) RAB9AMAPTNPC1LMNAALDH1A1
Hydrochloric Acid SCHEMBL11672960 1.00 RAB9A (0.75) RAB9AMAPTNPC1LMNAALDH1A1
Hydrochloric Acid SCHEMBL30705049 1.00 RAB9A (0.75) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL29372630 0.97 RAB9A (0.78) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL123584 0.97 RAB9A (0.78) RAB9AMAPTNPC1LMNAALDH1A1
Ammonia Solution, Strong SCHEMBL3418096 0.95 RAB9A (0.75) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL65503 0.90 RAB9A (0.76) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL29724705 0.90 RAB9A (0.76) RAB9AMAPTNPC1LMNAALDH1A1
Hydrochloric Acid SCHEMBL2867998 0.89 RAB9A (0.96) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL23989284 0.86 RAB9A (1.00) RAB9AMAPTNPC1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117275949-B Preparation method of graphene semiconductor heterogeneous solar cell material 深圳特新界面科技有限公司 2024-03-08 CN claimed
CN-117275949-A Preparation method of graphene semiconductor heterogeneous solar cell material 深圳特新界面科技有限公司 2023-12-22 CN claimed
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
EP-4493638-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-01-22 EP disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
CN-117275949-B Preparation method of graphene semiconductor heterogeneous solar cell material 深圳特新界面科技有限公司 2024-03-08 CN disclosed
CN-117275949-A Preparation method of graphene semiconductor heterogeneous solar cell material 深圳特新界面科技有限公司 2023-12-22 CN disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 CN disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
EP-0679183-B1 ENHANCEMENT OF ENZYME REACTIONS NOVOZYMES AS (DK) 2003-04-16 EP disclosed
US-5939088-A Sheets for animals, sheet, bags, daily goods, ink and packaging materials DAIKI CO., LTD. (JP) 1999-08-17 US disclosed
US-5821320-A MIXING AROMATIC DIAMINE DIHYDROCHLORIDE OR SULFATE WITH AROMATIC ACID DIANHYDRIDE, HEATING TO DEHYDRATE AND CONDENSE PETROLEUM ENERGY CENTER (JP) 1998-10-13 US disclosed
US-5814327-A Sheets for animals, sheet, bags, daily goods, ink and packaging materials DAIKI CO., LTD. (JP) 1998-09-29 US disclosed
EP-0510195-B1 Layered sheet for testing urine DAIKI KK (JP) 1997-06-04 EP disclosed
EP-0765599-A2 Toilet sand foor animals DAIKI CO., LTD (JP) 1997-04-02 EP disclosed
US-5595754-A Sheets for animals, sheet, bags, daily goods, ink and packaging materials DAIKI CO., LTD. (JP) 1997-01-21 US disclosed
EP-0510195-A1 SHEET, SEAT, BAG, ARTICLE OF DAILY USE, INK AND PACKAGING MATERIAL FOR ANIMAL DAIKI CO., LTD (JP) 1992-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD GAA 2511/4885PARP1 26/4885KCNH2 4377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.