Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804333 | 0.92 | KLK7 (0.39) | CYP11B1CYP11B2MEN1KMT2AKLK7 | |
| SCHEMBL6669306 | 0.89 | HTR2A (0.40) | EIF2AK3SYKMAPTRIPK1NPC1 | |
| SCHEMBL6669273 | 0.88 | CYP11B1 (0.44) | CYP11B1CYP11B2MEN1KMT2AKLK7 | |
| SCHEMBL6804782 | 0.87 | MAPT (0.43) | EIF2AK3POLBSYKCREBBPMAPT | |
| SCHEMBL6667760 | 0.86 | EIF2AK3 (0.47) | CYP11B1CYP11B2MEN1KMT2AEIF2AK3 | |
| SCHEMBL6804557 | 0.84 | SMO (0.47) | SMN1; SMN2SMO | |
| SCHEMBL6666486 | 0.84 | EIF2AK3 (0.41) | CYP11B1CYP11B2MEN1KMT2AKLK7 | |
| SCHEMBL6671845 | 0.81 | CYP11B1 (0.43) | CYP11B1CYP11B2EIF2AK3POLBEIF2AK1 | |
| SCHEMBL6803618 | 0.81 | RIPK1 (0.40) | CYP11B1CYP11B2MEN1KMT2AKLK7 | |
| SCHEMBL6805312 | 0.80 | EIF2AK3 (0.43) | CYP11B1CYP11B2KLK7EIF2AK3EIF2AK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |