Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 9/20 | 0.43 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804764 | 0.92 | MAPT (0.44) | EIF2AK3EIF2AK1CYP11B1CYP11B2RIPK1 | |
| SCHEMBL6669273 | 0.92 | CYP11B1 (0.44) | EIF2AK3EIF2AK1CYP11B1CYP11B2RIPK1 | |
| SCHEMBL6803323 | 0.89 | EIF2AK3 (0.43) | EIF2AK3EIF2AK1CYP11B1CYP11B2RIPK1 | |
| SCHEMBL6809825 | 0.89 | SMO (0.50) | RIPK1SMO | |
| SCHEMBL6804333 | 0.88 | KLK7 (0.39) | EIF2AK3EIF2AK1CYP11B1CYP11B2RIPK1 | |
| SCHEMBL6672281 | 0.88 | EIF2AK3 (0.49) | EIF2AK3CYP11B1CYP11B2CREBBPROCK2 | |
| SCHEMBL6671845 | 0.85 | CYP11B1 (0.43) | EIF2AK3EIF2AK1CYP11B1CYP11B2RIPK1 | |
| SCHEMBL6803618 | 0.84 | RIPK1 (0.40) | EIF2AK3CYP11B1CYP11B2RIPK1CREBBP | |
| SCHEMBL6667572 | 0.82 | HTR2A (0.43) | EIF2AK3EIF2AK1CYP11B1CYP11B2RIPK1 | |
| SCHEMBL6803784 | 0.82 | EIF2AK3 (0.53) | EIF2AK3EIF2AK1CYP11B1CYP11B2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | claimed |
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | EIF2AK3 2638/4885EIF2AK1 2837/4885CYP11B1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.