SCHEMBL6665985

SCHEMBL6665985

O=C1C=CC(=O)C(c2c(S(=O)(=O)O)ccc3c2ccc2ccccc23)=C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
ALOX12 P18054 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 1/20 0.48
HIF1A Q16665 1/20 0.48
HKDC1 Q2TB90 2/20 0.40
CCR6 P51684 1/20 0.40
CES1 P23141 1/20 0.39
CTRB1 P17538 1/20 0.39
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7912462 0.81 CYP1A2 (0.53) ALDH1A1HPGDCYP1A2CYP2C19MEN1
SCHEMBL11577947 0.78 CYP1A2 (0.53) ALDH1A1HPGDCYP1A2CYP2C19MEN1
SCHEMBL7915491 0.78 ALDH1A1 (0.53) ALDH1A1HPGDCYP1A2CYP2C19MEN1
SCHEMBL7914952 0.78 ALDH1A1 (0.53) ALDH1A1HPGDCYP1A2CYP2C19MEN1
SCHEMBL7905047 0.78 ALDH1A1 (0.53) ALDH1A1HPGDCYP1A2CYP2C19MEN1
Benzoquinone SCHEMBL4176250 0.77 HPRT1 (0.44) ALDH1A1HPGDCYP1A2CYP2C19MEN1
SCHEMBL51777 0.74 ALDH1A1 (0.54) ALDH1A1HPGDCYP1A2CYP2C19MEN1
SCHEMBL28569068 0.74 ALDH1A1 (0.54) ALDH1A1HPGDCYP1A2CYP2C19MEN1
SCHEMBL2380017 0.74 ALDH1A1 (0.54) ALDH1A1HPGDCYP1A2CYP2C19MEN1
SCHEMBL2700202 0.74 HPRT1 (0.51) ALDH1A1HPGDCYP1A2CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004014874-A1 ANISOTROPIC FILMS BASED ON SULFODERIVATIVES OF PHENANTHRO-9’,10’:2,3-QUINOXALINE AND LYOTROPIC LIQUID CRYSTAL SYSTEM AND METHOD FOR MAKING OPTIVA, INC. (US) 2004-02-19 WO disclosed
US-6583284-B1 Stable; no significant visible light absorption OPTIVA, INC. 2003-06-24 US disclosed