SCHEMBL7905047

SCHEMBL7905047

O=C1C=CC(=O)C(c2c(Br)ccc3c2ccc2ccccc23)=C1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
MEN1 O00255 2/20 0.53
MAPK1 P28482 2/20 0.53
KMT2A Q03164 2/20 0.53
USP2 O75604 1/20 0.53
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
CYP2D6 P10635 1/20 0.53
HPGD P15428 1/20 0.53
ALOX12 P18054 1/20 0.53
HIF1A Q16665 1/20 0.53
HKDC1 Q2TB90 2/20 0.47
CCR6 P51684 1/20 0.47
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
HSD17B3 P37058 1/20 0.42
HPRT1 P00492 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28031782 0.92 HKDC1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL3290538 0.84 CCR6 (0.37) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL7912462 0.82 CYP1A2 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL7915491 0.82 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL11577947 0.82 CYP1A2 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL7914952 0.82 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL51777 0.78 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28569068 0.78 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL2380017 0.78 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL6665985 0.78 ALDH1A1 (0.48) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed