Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631237 | 0.83 | MMP1 (0.48) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL3720430 | 0.79 | MAOB (0.50) | RIPK1ALDH1A1TDP1MAPTLMNA | |
| SCHEMBL25840103 | 0.78 | MMP1 (0.49) | MMP1MMP2MMP9MMP12RIPK1 | |
| SCHEMBL1787181 | 0.77 | MMP1 (0.51) | MMP1MMP2MMP9MMP12RIPK1 | |
| SCHEMBL28220495 | 0.76 | MMP2 (0.44) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL9105956 | 0.76 | CYP4F2 (0.47) | RIPK1ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL1787182 | 0.76 | MMP1 (0.50) | MMP1MMP2MMP9MMP12RIPK1 | |
| SCHEMBL10181075 | 0.75 | ALOX15 (0.41) | RIPK1ALDH1A1LMNAKMT2A | |
| SCHEMBL17552783 | 0.75 | RIPK1 (0.55) | MMP1MMP2MMP9MMP12RIPK1 | |
| SCHEMBL25238748 | 0.74 | MMP1 (0.49) | MMP1MMP2MMP9MMP12RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |