SCHEMBL2291589

SCHEMBL2291589

O=C(OCc1ccc(O)cc1Cl)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.57
TDP1 Q9NUW8 3/20 0.53
KMT2A Q03164 2/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
LMNA P02545 1/20 0.53
PPARG P37231 1/20 0.51
RAB9A P51151 3/20 0.50
MAPT P10636 2/20 0.50
POLB P06746 1/20 0.49
NPSR1 Q6W5P4 2/20 0.48
NPC1 O15118 2/20 0.48
ALDH1A1 P00352 1/20 0.48
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MAPK1 P28482 1/20 0.48
HSP90AA1 P07900 1/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666901 0.88 L3MBTL1 (0.74) L3MBTL1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL10611790 0.84 KMT2A (0.56) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL5421974 0.83 L3MBTL1 (0.72) L3MBTL1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL831262 0.81 MAPT (0.68) L3MBTL1TDP1KMT2ALMNAPPARG
SCHEMBL29074347 0.81 HSP90AA1 (0.61) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL11901965 0.79 KMT2A (0.58) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL5085480 0.77 PPARG (0.71) L3MBTL1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL14129928 0.77 MAPT (0.63) L3MBTL1TDP1KMT2ALMNARAB9A
SCHEMBL17537989 0.76 TDP1 (0.63) L3MBTL1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL7542989 0.76 NR4A2 (0.68) L3MBTL1TDP1KMT2ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7993732-B2 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2011-08-09 US disclosed
US-7989389-B2 Heat-sensitive recording material RICOH COMPANY, LTD. (JP) 2011-08-02 US disclosed
US-20090176647-A1 HEAT-SENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-07-09 US disclosed
US-20080026205-A1 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2008-01-31 US disclosed
EP-1882726-A1 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material Ricoh Company, Ltd. (JP) 2008-01-30 EP disclosed