SCHEMBL6667152

SCHEMBL6667152

CCCc1ccc(COC(F)(F)Cc2ccc(C(F)(F)F)c(F)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.40
DAO P14920 1/20 0.39
FFAR1 O14842 1/20 0.38
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
P2RX7 Q99572 1/20 0.33
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
FFAR4 Q5NUL3 1/20 0.32
HSD11B1 P28845 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666308 0.91 ESR1 (0.40) KIF11DAOFFAR1HSD11B1
SCHEMBL6667082 0.90 KIF11 (0.41) KIF11DAOFFAR1PPARGPPARD
SCHEMBL6665134 0.87 MAOA (0.35) GPR84SENP8SENP7SENP6MAOB
SCHEMBL6665750 0.86 GPR84 (0.35) DAOGPR84SENP8SENP7SENP6
SCHEMBL6662183 0.85 GPR84 (0.34) GPR84SENP8SENP7SENP6MAOB
SCHEMBL13002669 0.83 DAO (0.52) KIF11DAOFFAR1P2RX7
SCHEMBL12143530 0.83 DAO (0.51) KIF11DAOFFAR1P2RX7
SCHEMBL6661132 0.83 LPL (0.38) GPR84
SCHEMBL6663209 0.81 GPR84 (0.32) GPR84FFAR4SENP8SENP7SENP6
SCHEMBL6666745 0.81 PDE2A (0.37) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed