Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667765 | 0.90 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL6666245 | 0.85 | KMT2A (0.49) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11067262 | 0.83 | KDM4E (0.80) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL11406037 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL5681631 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL6664554 | 0.79 | ALDH1A1 (0.74) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL6666247 | 0.78 | KMT2A (0.51) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11064244 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL10920758 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL11026160 | 0.75 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDHSD17B10DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | disclosed |