Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 10/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573278 | 0.90 | CTSL (0.54) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| SCHEMBL6669674 | 0.89 | TDP1 (0.55) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| SCHEMBL6664653 | 0.87 | MMP2 (0.52) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| SCHEMBL6666012 | 0.87 | MMP2 (0.52) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| SCHEMBL6667278 | 0.85 | MMP2 (0.52) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| Hydrochloric Acid SCHEMBL28872216 | 0.83 | MMP2 (0.75) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| SCHEMBL697476 | 0.83 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| SCHEMBL1203540 | 0.83 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| SCHEMBL697477 | 0.83 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4MMP3 | |
| Hydrochloric Acid SCHEMBL3839410 | 0.82 | MMP2 (0.77) | MMP9TDP1MMP2ADAMTS4MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014882-A2 | PROTEASOME INHIBITORS : PEPTIDE DERIVATIVES HAVING C-TERMINAL HETEROARYL GROUPS | AXYS PHARMACEUTICALS (US) | 2004-02-19 | — | — | WO | disclosed |