Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.52 |
| ▸ | MMP13 | P45452 | 4/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666012 | 1.00 | MMP2 (0.52) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL6667278 | 0.89 | MMP2 (0.52) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL6667307 | 0.87 | MMP9 (0.57) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL6669674 | 0.81 | TDP1 (0.55) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL8345283 | 0.78 | KDM4E (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5573278 | 0.78 | CTSL (0.54) | MMP2MMP13MMP3TDP1MMP9 | |
| Hydrochloric Acid SCHEMBL28872216 | 0.75 | MMP2 (0.75) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL697476 | 0.75 | MMP2 (0.79) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL697477 | 0.75 | MMP2 (0.79) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL1203540 | 0.75 | MMP2 (0.79) | MMP2MMP13MMP3TDP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014882-A2 | PROTEASOME INHIBITORS : PEPTIDE DERIVATIVES HAVING C-TERMINAL HETEROARYL GROUPS | AXYS PHARMACEUTICALS (US) | 2004-02-19 | — | — | WO | disclosed |