Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 13/20 | 0.34 |
| ▸ | NOS3 | P29474 | 9/20 | 0.34 |
| ▸ | NOS2 | P35228 | 8/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641025 | 0.75 | HTR1F (0.71) | HTR1F | |
| SCHEMBL8547804 | 0.72 | NPC1 (0.41) | HTR1FCDK9DYRK1ADYRK2HTR6 | |
| SCHEMBL6643191 | 0.72 | HTR1A (0.46) | NOS1NOS3NOS2HTR6HTR1A | |
| SCHEMBL6641956 | 0.71 | HTR1F (0.81) | HTR1F | |
| Oxalic Acid SCHEMBL6646761 | 0.71 | HTR1F (0.65) | HTR1FHTR6HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL8553027 | 0.71 | NPC1 (0.40) | HTR1FCDK9DYRK1ADYRK2HTR6 | |
| Oxalic Acid SCHEMBL6804728 | 0.67 | HTR1F (0.94) | HTR1FHTR6HTR1AHTR2C | |
| SCHEMBL3758641 | 0.66 | NOS1 (0.36) | HTR1FNOS1NOS3NOS2PTPN1 | |
| SCHEMBL24756923 | 0.62 | NOS3 (0.43) | NOS1NOS3NOS2CDK9DYRK1A | |
| SCHEMBL29814450 | 0.62 | TAAR1 (0.42) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155020-B1 | FURO[3,2-B]PYRIDINES AS 5-HT1F AGONISTS | LILLY CO ELI (US) | 2004-02-04 | — | — | EP | disclosed |