Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935060 | 0.90 | ALDH1A1 (0.60) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL11171190 | 0.82 | ALDH1A1 (0.59) | KDM4EALDH1A1L3MBTL1MAPTATM | |
| SCHEMBL8294664 | 0.82 | KMT2A (0.51) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL7010720 | 0.82 | SMN1; SMN2 (0.53) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL6991991 | 0.82 | SLC6A1 (0.49) | MEN1KMT2ASLC6A1 | |
| SCHEMBL16012677 | 0.82 | SLC6A1 (0.49) | MEN1KMT2ASLC6A1 | |
| SCHEMBL11709792 | 0.81 | LMNA (0.45) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL11717512 | 0.81 | LMNA (0.45) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL11712424 | 0.81 | LMNA (0.45) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL8555290 | 0.81 | LMNA (0.51) | KDM4EALDH1A1L3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013143-A2 | AZA-BRIDGED BICYCLIC AMINE DERIVATIVES FOR USE AS NOVEL CHOLINERGIC RECEPTOR LIGANDS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2004-02-12 | — | — | WO | disclosed |