Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29241053 | 0.82 | KEAP1 (0.50) | L3MBTL1KEAP1NFE2L2KMT2AMEN1 | |
| SCHEMBL10688703 | 0.82 | ALDH1A1 (0.51) | L3MBTL1KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL7194392 | 0.80 | KEAP1 (0.57) | L3MBTL1KEAP1NFE2L2KMT2AHTT | |
| SCHEMBL10514057 | 0.79 | APEX1 (0.64) | KEAP1NFE2L2KMT2AMEN1HTT | |
| SCHEMBL9724058 | 0.79 | L3MBTL1 (0.72) | L3MBTL1KMT2AHTTPOLB | |
| SCHEMBL13164003 | 0.77 | KEAP1 (0.50) | L3MBTL1KEAP1NFE2L2KMT2AMEN1 | |
| SCHEMBL5763362 | 0.77 | KEAP1 (0.51) | KEAP1NFE2L2KMT2AMEN1HTT | |
| SCHEMBL6911920 | 0.76 | ALDH1A1 (0.54) | L3MBTL1KEAP1NFE2L2KMT2AMEN1 | |
| SCHEMBL29241051 | 0.75 | KEAP1 (0.50) | L3MBTL1KEAP1NFE2L2KMT2AHTT | |
| SCHEMBL2068996 | 0.75 | FFAR1 (0.51) | KEAP1NFE2L2KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140515-B1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SC HOLDING AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| US-6624117-B1 | Heat sensitive recording material | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | disclosed |
| EP-1140515-A1 | HEAT SENSITIVE RECORDING MATERIAL | Ciba SC Holding AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035679-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-06-22 | — | — | WO | disclosed |