Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671971 | 0.88 | ALDH1A1 (0.52) | ALDH1A1HSD17B10GAASLC6A2SLC6A4 | |
| SCHEMBL10572679 | 0.85 | UTS2R (0.51) | ALDH1A1GAA | |
| SCHEMBL28580616 | 0.84 | AKR1C3 (0.53) | MEN1KMT2AALOX15 | |
| SCHEMBL5487618 | 0.83 | CHRM1 (0.52) | ALDH1A1HSD17B10GAASLC6A2SLC6A4 | |
| SCHEMBL491226 | 0.83 | ALOX15 (0.48) | MEN1KMT2AALOX15HPGD | |
| SCHEMBL21342451 | 0.81 | ALOX15 (0.47) | ALDH1A1HSD17B10GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL21331948 | 0.80 | ALOX15 (0.46) | ALDH1A1HSD17B10GAASLC6A2SLC6A4 | |
| SCHEMBL6390492 | 0.80 | FFAR1 (0.50) | KMT2AALOX15HPGD | |
| SCHEMBL1244581 | 0.80 | ALOX15 (0.52) | ALDH1A1HTTKMT2AALOX15HPGD | |
| SCHEMBL1069511 | 0.80 | LMNA (0.60) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213279-B1 | VENLAFAXINE PRODUCTION PROCESS | MEDICHEM SA (ES) | 2004-09-15 | — | — | EP | disclosed |
| US-6506941-B1 | Venlafaxine production process | MEDICHEM, S.A. (ES) | 2003-01-14 | — | — | US | disclosed |
| EP-1213279-A1 | VENLAFAXINE PRODUCTION PROCESS | Medichem S.A. (ES) | 2002-06-12 | — | — | EP | disclosed |