Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667892 | 0.88 | ALDH1A1 (0.50) | ALDH1A1HSD17B10GAASLC6A2SLC6A4 | |
| SCHEMBL2685869 | 0.83 | L3MBTL1 (0.46) | ALDH1A1HSD17B10GAAMEN1CYP2D6 | |
| SCHEMBL17877688 | 0.83 | L3MBTL1 (0.46) | ALDH1A1HSD17B10GAAMEN1KMT2A | |
| SCHEMBL27146207 | 0.81 | AKR1C3 (0.54) | ALDH1A1MEN1KMT2AESR1ESR2 | |
| SCHEMBL25241435 | 0.81 | GPR88 (0.51) | MEN1HTTKMT2AAOC3ESR1 | |
| SCHEMBL1069341 | 0.81 | LTA4H (0.53) | — | |
| SCHEMBL28177712 | 0.80 | ESR1 (0.49) | MEN1KMT2AAOC3ESR1ESR2 | |
| SCHEMBL19986352 | 0.79 | SLC6A3 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6AOC3 | |
| SCHEMBL6390486 | 0.79 | L3MBTL1 (0.48) | ALDH1A1GAAMEN1HTTKMT2A | |
| SCHEMBL8585874 | 0.79 | FFAR1 (0.52) | GAAHTTKMT2ALMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213279-B1 | VENLAFAXINE PRODUCTION PROCESS | MEDICHEM SA (ES) | 2004-09-15 | — | — | EP | disclosed |
| US-6506941-B1 | Venlafaxine production process | MEDICHEM, S.A. (ES) | 2003-01-14 | — | — | US | disclosed |
| EP-1213279-A1 | VENLAFAXINE PRODUCTION PROCESS | Medichem S.A. (ES) | 2002-06-12 | — | — | EP | disclosed |