SCHEMBL6668232

SCHEMBL6668232

CC#CC(C)(COC)NC(=O)CC(OC)Oc1cncc(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
HTRA1 Q92743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671901 0.82 HTRA1 (0.32) MAPTKMT2AHTRA1
SCHEMBL5160573 0.81 HTRA1 (0.32) HTRA1
SCHEMBL6671605 0.73 PKM (0.31) MAPTKMT2A
SCHEMBL5158389 0.72 PKM (0.35) MAPTKMT2A
SCHEMBL5160918 0.72 HTRA1 (0.35) HTRA1
SCHEMBL6673612 0.71 PKM (0.33) MAPTKMT2A
SCHEMBL6249581 0.71 TSHR (0.32)
SCHEMBL5160452 0.70 PKM (0.35)
SCHEMBL6252988 0.69 HTRA1 (0.31) HTRA1
SCHEMBL5158505 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456174-A1 PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES Syngenta Limited (GB) 2004-09-15 EP disclosed
WO-2003048128-A1 PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES SYNGENTA LIMITED (GB) 2003-06-12 WO disclosed