SCHEMBL6669074

SCHEMBL6669074

Cc1c(-c2ccc3c(c2)CNC3C)ccn2c(=O)c(C(=O)O)cc(C3CC3)c12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 1/20 0.33
CAMKK2 Q96RR4 3/20 0.32
CAMKK1 Q8N5S9 2/20 0.32
PIK3CG P48736 1/20 0.31
NOTUM Q6P988 1/20 0.31
KDM6B O15054 2/20 0.30
KDM4C Q9H3R0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6673956 0.88 CAMKK1 (0.30) CAMKK2CAMKK1
SCHEMBL6669852 0.86 CAMKK2 (0.33) CD274CAMKK2CAMKK1PIK3CGNOTUM
SCHEMBL12502114 0.82 CLK4 (0.40) CAMKK2CAMKK1
SCHEMBL1290218 0.82 KDM4E (0.38) CAMKK2CAMKK1NOTUMKDM4C
SCHEMBL5417688 0.82 CAMKK2 (0.35) CAMKK2CAMKK1NOTUM
SCHEMBL15261957 0.81 CAMKK2 (0.33) CAMKK2CAMKK1PIK3CGKDM6BKDM4C
SCHEMBL1290113 0.81 KDM4E (0.34) CAMKK2CAMKK1NOTUM
SCHEMBL1290026 0.81 HSD17B10 (0.38) CAMKK2CAMKK1NOTUM
Hydrochloric Acid SCHEMBL12502378 0.81 CAMKK2 (0.33) CAMKK2CAMKK1PIK3CGKDM6BKDM4C
SCHEMBL12501950 0.81 BAZ2B (0.37) CAMKK2CAMKK1NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1227096-B1 4-OXOQUINOLIZINE ANTIMICROBIALS HAVING 2-PYRIDONE SKELETONS AS THE PARTIAL STRUCTURE SATO PHARMA (JP) 2004-09-22 EP disclosed
US-6525066-B2 Bactericides; side effect reduction SATO PHARMACEUTICAL CO., LTD. (JP) 2003-02-25 US disclosed
US-20020173517-A1 4-Oxoquinolizine antimicrobial having 2-pyridone skeleton as partial structure SATO PHARMACEUTICAL CO., LTD. (JP) 2002-11-21 US disclosed
EP-1227096-A1 4-OXOQUINOLIZINE ANTIMICROBIALS HAVING 2-PYRIDONE SKELETONS AS THE PARTIAL STRUCTURE Sato Pharmaceutical Co. Ltd. (JP) 2002-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173517-A1 4-Oxoquinolizine antimicrobial having 2-pyridone skeleton as partial structure IL4I1, TLR5, IFNG CD274 1503/4885CAMKK2 3507/4885CAMKK1 3356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.