SCHEMBL6669941

SCHEMBL6669941

CCCCC(O)C(CC)C/C=C(\C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.38
MAPK1 P28482 1/20 0.38
LMNA P02545 1/20 0.35
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35
GPR84 Q9NQS5 5/20 0.33
CA1 P00915 3/20 0.33
FFAR1 O14842 1/20 0.33
FPR2 P25090 2/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
EP300 Q09472 1/20 0.33
LCK P06239 1/20 0.33
PPARD Q03181 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671090 0.90 ACHE (0.35) CA2MAPK1LMNAACHEBACE1
SCHEMBL149321 0.90 LMNA (0.46) LMNA
SCHEMBL149319 0.90 LMNA (0.46) LMNA
SCHEMBL6670815 0.82 ACHE (0.36) CA2MAPK1ACHEBACE1GPR84
SCHEMBL17006681 0.81 CA2 (0.39) CA2MAPK1ACHEBACE1GPR84
SCHEMBL12076392 0.80 GPR84 (0.43) CA2MAPK1ACHEBACE1GPR84
SCHEMBL613229 0.80 GPR84 (0.43) CA2MAPK1ACHEBACE1GPR84
SCHEMBL15051281 0.78 CA2 (0.37) CA2MAPK1ACHEBACE1GPR84
SCHEMBL22168 0.78 CA2 (0.44) CA2MAPK1CA1EP300LCK
SCHEMBL22166 0.78 CA2 (0.44) CA2MAPK1CA1EP300LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP claimed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP claimed