Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672519 | 0.80 | GRM5 (0.39) | KDM4EGRM5CYP11B1CYP11B2LTA4H | |
| SCHEMBL29442825 | 0.70 | MEN1 (0.47) | P2RX7MEN1KMT2AMAPTPABPC1 | |
| SCHEMBL28701298 | 0.70 | MEN1 (0.47) | P2RX7MEN1KMT2AMAPTPABPC1 | |
| SCHEMBL24833581 | 0.68 | GRIN2B (0.46) | MEN1KMT2AMAPTPABPC1ALDH1A1 | |
| SCHEMBL30862000 | 0.67 | NR1D1 (0.48) | MEN1KMT2AMAPTPABPC1KDM4E | |
| SCHEMBL3512964 | 0.67 | NR1D1 (0.48) | MEN1KMT2AMAPTPABPC1KDM4E | |
| SCHEMBL7673699 | 0.67 | NR1D1 (0.48) | KDM4EALDH1A1CYP11B1CYP11B2NR1D1 | |
| SCHEMBL29442877 | 0.67 | CYP17A1 (0.56) | KDM4EALDH1A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL727185 | 0.66 | CYP1A2 (0.62) | TDP1CYP11B1CYP11B2TBXAS1CHRNA7 | |
| SCHEMBL10487072 | 0.66 | PKM (0.51) | KMT2AALDH1A1GRM5CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030637-A2 | TREATMENT OF OBESITY AND OTHER DISORDERS ASSOCIATED WITH EXCESSIVE FOOD INTAKE | MERCK & CO., INC. (US) | 2004-04-15 | — | — | WO | claimed |