Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548939 | 0.83 | RAB9A (0.48) | ALDH1A1GFERPOLBCASP3SENP8 | |
| SCHEMBL15452667 | 0.82 | ALDH1A1 (0.51) | ALDH1A1GFERPOLBPRSS1PRSS2 | |
| SCHEMBL25100436 | 0.81 | CYP2C19 (0.51) | ALDH1A1GFERPOLBCASP3SENP8 | |
| SCHEMBL16370141 | 0.81 | MAPT (0.57) | ALDH1A1GFERPOLBCASP3SENP8 | |
| SCHEMBL24988733 | 0.81 | ALDH1A1 (0.45) | ALDH1A1GFERPOLBCASP3SENP8 | |
| SCHEMBL16370140 | 0.81 | MAPT (0.57) | ALDH1A1GFERPOLBCASP3SENP8 | |
| SCHEMBL12585063 | 0.78 | ALOX15 (0.50) | GFERPOLBCASP3SENP8SENP7 | |
| SCHEMBL18310621 | 0.78 | GFER (0.42) | ALDH1A1GFERPOLBCASP3SENP8 | |
| SCHEMBL12360950 | 0.77 | CA9 (0.52) | ALDH1A1GFERPOLBCASP3SENP8 | |
| SCHEMBL14298196 | 0.77 | CA9 (0.52) | ALDH1A1GFERPOLBCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642748-B | O- (2-trifluoromethyl-2-hydroxyethyl) oxime ether derivative and synthetic method and application thereof | 华南理工大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-109651191-B | Difluoromethyl oxime ether derivative and synthetic method thereof | 华南理工大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-110642748-A | O- (2-trifluoromethyl-2-hydroxyethyl) oxime ether derivative and synthetic method and application thereof | 华南理工大学 | 2020-01-03 | — | — | CN | disclosed |
| EP-1133467-B1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH AS (DK) | 2004-09-15 | — | — | EP | disclosed |